22 - 21

(Oct 5, 2025 · Week 05)

Eager to return to the winning ways that left them undefeated over their season’s first two weeks, the Kyler Murray-led Cardinals arrived to Week 5 with a sense of urgency from the opening drive. Often poised for something truly must-see whenever throwing on the run, Murray got Arizona’s home crowd involved early, giving his 6-foot-3 star receiver an opportunity — against double coverage no less — for a 44-yard connection. The Tennessee Titans’ late-game execution encouraged a come-from-behind 22-21 win on Oct. 5, 2025, but Murray was nevertheless efficient in defeat, pairing a 220-yard passing effort (on 23-of-31) with four carries, 25 yards, and a touchdown run.

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